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1.    VPCs are specific to a region, so you should select the same region in which you created your key pair.

2.    Security groups act as a firewall for associated instances, controlling both inbound and outbound traffic at the instance level. 

3.    Note that if you plan to launch instances in multiple regions, you'll need to create a security group in each region.

4.    Security Group:  Source is set to anywhere using IP 0.0.0.0/0.

5.    Security Group: To specify an individual IP address in CIDR notation, add the routing prefix /32. For example, if your IP address is 203.0.113.25, specify 203.0.113.25/32. If your company allocates addresses from a range, specify the entire range, such as 203.0.113.0/24.

6.    Don't select the Proceed without a key pair option. If you launch your instance without a key pair, then you can't connect to it.